http://content.nejm.org/Browse NEJM’s most-viewed clinical and medical articles to see what your colleagues are viewing most often. These clinical and medical articles are listed in rank order, and the list is updated daily.http://content.nejm.org/icons/nejm_name_220.gifhttp://content.nejm.org/Sun, 22 Nov 2009 06:30:02 GMTThe New England Journal of Medicine is owned, published, and copyrighted © 2009 Massachusetts Medical Society. All rights reserved.en-usThe idiopathic inflammatory bowel diseases comprise two types of chronic intestinal disorders: Crohn's disease and ulcerative colitis. Accumulating evidence suggests that inflammatory bowel disease results from an inappropriate inflammatory response...http://content.nejm.org/cgi/content/short/361/21/2066?ssource=mfvReview ArticleClara Abraham, M.D., and Judy H. Cho, M.D.Thu, 19 Nov 2009 00:00:00 GMThttp://content.nejm.org/cgi/content/short/361/21/2066?ssource=mfvA 77-year-old man presented with a 5-day history of painful swelling of his right elbow, which was also red, warm, and tender. When pressure was applied, a toothpastelike, white, chalky...http://content.nejm.org/cgi/content/short/361/21/e49?ssource=mfvImages in Clinical MedicineThomas Wiesner, M.D., Isabella Fried, M.D.Thu, 19 Nov 2009 00:00:00 GMThttp://content.nejm.org/cgi/content/short/361/21/e49?ssource=mfvDr. David T. Ting (Medical Oncology): A 23-year-old man was transferred to this hospital because of cough, hoarseness, fever, and abnormalities on chest imaging. The patient had been well until...http://content.nejm.org/cgi/content/short/361/21/2080?ssource=mfvCase Records of the Massachusetts General HospitalEdwin Choy, M.D., Ph.D., Subba R. Digumarthy, M.D., and Stephanie A. Koplin, M.D.Thu, 19 Nov 2009 00:00:00 GMThttp://content.nejm.org/cgi/content/short/361/21/2080?ssource=mfvA 31-year-old woman in the 37th week of pregnancy presented to the emergency room of another hospital with sudden onset of severe bitemporal headache and shortness of breath. She was...http://content.nejm.org/cgi/content/short/361/20/e45?ssource=mfvInteractive Medical CaseJohn J. Ross, M.D., Akshay S. Desai, M.D., William A. Chutkow, M.D., Katherine E. Economy, M.D., G. William Dec, Jr., M.D.Thu, 12 Nov 2009 00:00:00 GMThttp://content.nejm.org/cgi/content/short/361/20/e45?ssource=mfvA 73-year-old former smoker with a history of hypertension and dyslipidemia presents to the emergency department with shortness of breath. His blood pressure is 160/75 mm Hg, heart rate 60...http://content.nejm.org/cgi/content/short/361/20/1972?ssource=mfvClinical PracticeLance D. Dworkin, M.D., and Christopher J. Cooper, M.D.Thu, 12 Nov 2009 00:00:00 GMThttp://content.nejm.org/cgi/content/short/361/20/1972?ssource=mfvA 61-year-old man was referred for treatment of painless white lesions on his tongue that had appeared 1 month earlier. He had been treated with topical and systemic antifungal drugs...http://content.nejm.org/cgi/content/short/361/20/e44?ssource=mfvImages in Clinical MedicineEmili Masferrer, M.D., Anna Jucgla, M.D.Thu, 12 Nov 2009 00:00:00 GMThttp://content.nejm.org/cgi/content/short/361/20/e44?ssource=mfvBackground: Percutaneous revascularization of the renal arteries improves patency in atherosclerotic renovascular disease, yet evidence of a clinical benefit is limited. In a randomized, unblinded trial, we assigned 806...http://content.nejm.org/cgi/content/short/361/20/1953?ssource=mfvOriginal ArticleThe ASTRAL InvestigatorsThu, 12 Nov 2009 00:00:00 GMThttp://content.nejm.org/cgi/content/short/361/20/1953?ssource=mfvBackground: Anemia is associated with an increased risk of cardiovascular and renal events among patients with type 2 diabetes and chronic kidney disease. Although darbepoetin alfa can effectively increase hemoglobin...http://content.nejm.org/cgi/content/short/361/21/2019?ssource=mfvOriginal ArticleMarc A. Pfeffer, M.D., Ph.D., Emmanuel A. Burdmann, M.D., Ph.D., Chao-Yin Chen, Ph.D., Mark E. Cooper, M.D., Dick de Zeeuw, M.D., Ph.D., Kai-Uwe Eckardt, M.D., Jan M. Feyzi, M.S., Peter Ivanovich, M.D., Reshma Kewalramani, M.D., Andrew S. Levey, M.D., Eldrin F. Lewis, M.D., M.P.H., Janet B. McGill, M.D., John J.V. McMurray, M.D., Patrick Parfrey, M.D., Hans-Henrik Parving, M.D., Giuseppe Remuzzi, M.D., Ajay K. Singh, M.D., Scott D. Solomon, M.D., and Robert Toto, M.D., for the TREAT InvestigatorsThu, 19 Nov 2009 00:00:00 GMThttp://content.nejm.org/cgi/content/short/361/21/2019?ssource=mfvBackground: During the spring of 2009, a pandemic influenza A (H1N1) virus emerged and spread globally. We describe the clinical characteristics of patients who were hospitalized with 2009 H1N1 influenza...http://content.nejm.org/cgi/content/short/361/20/1935?ssource=mfvOriginal ArticleSeema Jain, M.D., Laurie Kamimoto, M.D., M.P.H., Anna M. Bramley, M.P.H., Ann M. Schmitz, D.V.M., Stephen R. Benoit, M.D., M.P.H., Janice Louie, M.D., M.P.H., David E. Sugerman, M.D., M.P.H., Jean K. Druckenmiller, B.S., S.M.(N.R.M.), Kathleen A. Ritger, M.D., M.P.H., Rashmi Chugh, M.D., M.P.H., Supriya Jasuja, M.D., M.P.H., Meredith Deutscher, M.D., Sanny Chen, Ph.D., M.H.S., John D. Walker, M.D., Jeffrey S. Duchin, M.D., Susan Lett, M.D., M.P.H., Susan Soliva, M.P.H., Eden V. Wells, M.D., M.P.H., David Swerdlow, M.D., Timothy M. Uyeki, M.D., M.P.H., Anthony E. Fiore, M.D., M.P.H., Sonja J. Olsen, Ph.D., Alicia M. Fry, M.D., M.P.H., Carolyn B. Bridges, M.D., Lyn Finelli, Dr.P.H., for the 2009 Pandemic Influenza A (H1N1) Virus Hospitalizations Investigation TeamThu, 12 Nov 2009 00:00:00 GMThttp://content.nejm.org/cgi/content/short/361/20/1935?ssource=mfvAberrant activation of the hedgehog pathway has been observed in multiple human cancers, including pancreatic cancer. For this reason, several small-molecule inhibitors of the pathway have been advanced to clinical...http://content.nejm.org/cgi/content/short/361/21/2094?ssource=mfvClinical Implications of Basic ResearchManuel Hidalgo, M.D., and Anirban Maitra, M.D.Thu, 19 Nov 2009 00:00:00 GMThttp://content.nejm.org/cgi/content/short/361/21/2094?ssource=mfv