http://content.nejm.org/Browse the NEJM articles that have been most widely covered in the press. Stay abreast of which NEJM articles the general public is hearing about most often in the media. These NEJM articles cover a range of topics. Articles are listed in rank order, and the list is updated weekly.http://content.nejm.org/icons/nejm_name_220.gifhttp://content.nejm.org/The New England Journal of Medicine is owned, published, and copyrighted © 2007 Massachusetts Medical Society. All rights reserved.en-usWed, 18 Nov 2009 00:00:00 GMTBackground: Treatment added to statin monotherapy to further modify the lipid profile may include combination therapy to either raise the high-density lipoprotein (HDL) cholesterol level or further lower the low-density...http://content.nejm.org/cgi/content/full/NEJMoa0907569?rss=1&ssource=mostCitedInMediaOriginal ArticleAllen J. Taylor, M.D., Todd C. Villines, M.D., Eric J. Stanek, Pharm.D., Patrick J. Devine, M.D., Len Griffen, M.D., Michael Miller, M.D., Neil J. Weissman, M.D., and Mark Turco, M.D.Sun, 15 Nov 2009 00:00:00 GMThttp://content.nejm.org/cgi/content/full/NEJMoa0907569?rss=1&ssource=mostCitedInMedia?rss=1&ssource=mostCitedInMediaBackground: Coronary-artery bypass grafting (CABG) has traditionally been performed with the use of cardiopulmonary bypass (on-pump CABG). CABG without cardiopulmonary bypass (off-pump CABG) might reduce the number of complications related...http://content.nejm.org/cgi/content/short/361/19/1827?rss=1&ssource=mostCitedInMediaOriginal ArticleA. Laurie Shroyer, Ph.D., Frederick L. Grover, M.D., Brack Hattler, M.D., Joseph F. Collins, Sc.D., Gerald O. McDonald, M.D., Elizabeth Kozora, Ph.D., John C. Lucke, M.D., Janet H. Baltz, R.N., and Dimitri Novitzky, M.D., Ph.D., for the Veterans Affairs Randomized On/Off Bypass (ROOBY) Study GroupThu, 05 Nov 2009 00:00:00 GMThttp://content.nejm.org/cgi/content/short/361/19/1827?rss=1&ssource=mostCitedInMedia?rss=1&ssource=mostCitedInMediaIn patients with elevated cholesterol levels, statin therapy reduces the incidence of cardiovascular events by 25 to 45%. Despite the administration of a statin, many patients require additional lipid-lowering therapy...http://content.nejm.org/cgi/content/full/NEJMe0908838?rss=1&ssource=mostCitedInMediaEditorialRoger S. Blumenthal, M.D., and Erin D. Michos, M.D., M.H.S.Sun, 15 Nov 2009 00:00:00 GMThttp://content.nejm.org/cgi/content/full/NEJMe0908838?rss=1&ssource=mostCitedInMedia?rss=1&ssource=mostCitedInMediaBackground: Vulvar intraepithelial neoplasia is a chronic disorder caused by high-risk types of human papillomavirus (HPV), most commonly HPV type 16 (HPV-16). Spontaneous regression occurs in less than 1.5% of...http://content.nejm.org/cgi/content/short/361/19/1838?rss=1&ssource=mostCitedInMediaOriginal ArticleGemma G. Kenter, M.D., Ph.D., Marij J.P. Welters, Ph.D., A. Rob P.M. Valentijn, Ph.D., Margriet J.G. Lowik, Dorien M.A. Berends-van der Meer, Annelies P.G. Vloon, Farah Essahsah, Lorraine M. Fathers, Rienk Offringa, Ph.D., Jan Wouter Drijfhout, Ph.D., Amon R. Wafelman, Ph.D., Jaap Oostendorp, Ph.D., Gert Jan Fleuren, M.D., Ph.D., Sjoerd H. van der Burg, Ph.D., and Cornelis J.M. Melief, M.D., Ph.D.Thu, 05 Nov 2009 00:00:00 GMThttp://content.nejm.org/cgi/content/short/361/19/1838?rss=1&ssource=mostCitedInMedia?rss=1&ssource=mostCitedInMediaBackground: Anemia is associated with an increased risk of cardiovascular and renal events among patients with type 2 diabetes and chronic kidney disease. Although darbepoetin alfa can effectively increase hemoglobin...http://content.nejm.org/cgi/content/short/361/21/2019?rss=1&ssource=mostCitedInMediaOriginal ArticleMarc A. Pfeffer, M.D., Ph.D., Emmanuel A. Burdmann, M.D., Ph.D., Chao-Yin Chen, Ph.D., Mark E. Cooper, M.D., Dick de Zeeuw, M.D., Ph.D., Kai-Uwe Eckardt, M.D., Jan M. Feyzi, M.S., Peter Ivanovich, M.D., Reshma Kewalramani, M.D., Andrew S. Levey, M.D., Eldrin F. Lewis, M.D., M.P.H., Janet B. McGill, M.D., John J.V. McMurray, M.D., Patrick Parfrey, M.D., Hans-Henrik Parving, M.D., Giuseppe Remuzzi, M.D., Ajay K. Singh, M.D., Scott D. Solomon, M.D., and Robert Toto, M.D., for the TREAT InvestigatorsThu, 19 Nov 2009 00:00:00 GMThttp://content.nejm.org/cgi/content/short/361/21/2019?rss=1&ssource=mostCitedInMedia?rss=1&ssource=mostCitedInMediaThe use of statin therapy to reduce levels of low-density lipoprotein (LDL) cholesterol in patients who are at high risk for vascular events results in a 30 to 40% reduction...http://content.nejm.org/cgi/content/full/NEJMe0908841?rss=1&ssource=mostCitedInMediaEditorialJohn J.P. Kastelein, M.D., Ph.D., and Michiel L. Bots, M.D., Ph.D.Sun, 15 Nov 2009 00:00:00 GMThttp://content.nejm.org/cgi/content/full/NEJMe0908841?rss=1&ssource=mostCitedInMedia?rss=1&ssource=mostCitedInMediaBackground: Patients with advanced heart failure have improved survival rates and quality of life when treated with implanted pulsatile-flow left ventricular assist devices as compared with medical therapy. New continuous-flow...http://content.nejm.org/cgi/content/full/NEJMoa0909938?rss=1&ssource=mostCitedInMediaOriginal ArticleMark S. Slaughter, M.D., Joseph G. Rogers, M.D., Carmelo A. Milano, M.D., Stuart D. Russell, M.D., John V. Conte, M.D., David Feldman, M.D., Ph.D., Benjamin Sun, M.D., Antone J. Tatooles, M.D., Reynolds M. Delgado, III, M.D., James W. Long, M.D., Ph.D., Thomas C. Wozniak, M.D., Waqas Ghumman, M.D., David J. Farrar, Ph.D., and O. Howard Frazier, M.D., for the HeartMate II InvestigatorsTue, 17 Nov 2009 00:00:00 GMThttp://content.nejm.org/cgi/content/full/NEJMoa0909938?rss=1&ssource=mostCitedInMedia?rss=1&ssource=mostCitedInMediaBackground: There is good evidence of selective outcome reporting in published reports of randomized trials. We examined reporting practices for trials of gabapentin funded by Pfizer and Warner-Lambert's subsidiary,...http://content.nejm.org/cgi/content/short/361/20/1963?rss=1&ssource=mostCitedInMediaSpecial ArticleS. Swaroop Vedula, M.D., M.P.H., Lisa Bero, Ph.D., Roberta W. Scherer, Ph.D., and Kay Dickersin, Ph.D.Thu, 12 Nov 2009 00:00:00 GMThttp://content.nejm.org/cgi/content/short/361/20/1963?rss=1&ssource=mostCitedInMedia?rss=1&ssource=mostCitedInMediaBackground: Cangrelor, a nonthienopyridine adenosine triphosphate analogue, is an intravenous blocker of the adenosine diphosphate receptor P2Y . This agent might have a role in the treatment of patients who...http://content.nejm.org/cgi/content/full/NEJMoa0908628?rss=1&ssource=mostCitedInMediaOriginal ArticleRobert A. Harrington, M.D., Gregg W. Stone, M.D., Steven McNulty, M.S., Harvey D. White, D.Sc., A. Michael Lincoff, M.D., C. Michael Gibson, M.D., Charles V. Pollack, Jr., M.D., Gilles Montalescot, M.D., Ph.D., Kenneth W. Mahaffey, M.D., Neal S. Kleiman, M.D., Shaun G. Goodman, M.D., Maged Amine, M.D., Dominick J. Angiolillo, M.D., Ph.D., Richard C. Becker, M.D., Derek P. Chew, M.B., B.S., M.P.H., William J. French, M.D., Franz Leisch, M.D., Keyur H. Parikh, M.D., Simona Skerjanec, Pharm.D., and Deepak L. Bhatt, M.D., M.P.H.Sun, 15 Nov 2009 00:00:00 GMThttp://content.nejm.org/cgi/content/full/NEJMoa0908628?rss=1&ssource=mostCitedInMedia?rss=1&ssource=mostCitedInMediaBackground: Intravenous cangrelor, a rapid-acting, reversible adenosine diphosphate (ADP) receptor antagonist, might reduce ischemic events during percutaneous coronary intervention (PCI). In this double-blind, placebo-controlled study, we randomly assigned 5362...http://content.nejm.org/cgi/content/full/NEJMoa0908629?rss=1&ssource=mostCitedInMediaOriginal ArticleDeepak L. Bhatt, M.D., M.P.H., A. Michael Lincoff, M.D., C. Michael Gibson, M.D., Gregg W. Stone, M.D., Steven McNulty, M.S., Gilles Montalescot, M.D., Ph.D., Neal S. Kleiman, M.D., Shaun G. Goodman, M.D., Harvey D. White, D.Sc., Kenneth W. Mahaffey, M.D., Charles V. Pollack, Jr., M.D., Steven V. Manoukian, M.D., Petr Widimsky, M.D., Dr.Sc., Derek P. Chew, M.B., B.S., M.P.H., Fernando Cura, M.D., Ivan Manukov, M.D., Frantisek Tousek, M.D., M. Zubair Jafar, M.D., Jaspal Arneja, M.D., Simona Skerjanec, Pharm.D., and Robert A. Harrington, M.D., for the CHAMPION PLATFORM InvestigatorsSun, 15 Nov 2009 00:00:00 GMThttp://content.nejm.org/cgi/content/full/NEJMoa0908629?rss=1&ssource=mostCitedInMedia?rss=1&ssource=mostCitedInMedia